Talk:Remifentanil

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I added cleanup-verify because a "clearance of 4,000 mL/min" and "effects [including] a 20% decrease in heart rate and arterial pressure" sound sketchy. mL/min sounds like a units error, and 20% at what dosage and in what type of patient? I don't know. Neurophyre 04:43, 24 Mar 2005 (UTC)

mL/min is an appropriate unit for drug clearance (meaning that 4000mL of blood is cleared of drug every minute), although perhaps 4L/min would be more appropriate. 20th June 2005

I have changed effects to reflect manufacturers package insert. The statement including 20% was inaccurate as you noted so I substituted the phrase "dose dependent" also consistent with manufacturers package insert. You are right remifentanil at high doses can cause a 100% decrease in heart rate and bp. Also the drugs renal clearance has very little to do with rapid resolution of effects so I deleted it (also clearance is 40ml/kg/min so 4000 was an approximation. BTW I am an anesthesiologist Stblndr 15:25, 27 July 2005 (UTC)[reply]

The side effects should include bradycardia and hypotension too, the latter used to good therapeutic effect. Jkbayley (talk) 13:58, 4 September 2009 (UTC)[reply]

ball and stick projection of the molecule

The ball and stick projection of the molecule is incorrect. There should't be the aromatic ring which we can see on the left side. 2A02:A316:6146:6E00:5DCA:9525:A1BE:A1F (talk) 08:24, 22 February 2023 (UTC)[reply]

Dead ref link

Remifentanil - Wikipedia

(cite 1) is broken where the Brazilian/Portuguese website is down, checked with downforeveryoneorjustme too.

I'm posting it on this talk page, and on the other one, because the mistake is duplicated on another opioid article here: Alfentanil - Wikipedia W;ChangingUsername (talk) 22:54, 20 October 2024 (UTC)[reply]